Carbonic anhydrase 3 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P07451. Use UniProt P07451 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P07451 as the stable identity anchor, then attach disease evidence before program review.
Carbonic anhydrase 3
Review this target as Carbonic anhydrase 3, mapped to UniProt P07451. Sequence length is 260 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Carbonic anhydrase 3 as ChEMBL target CHEMBL2885, mapped to UniProt P07451. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Carbonic anhydrase 3 is the right protein anchor across sources, using UniProt P07451 as the stable mapping.
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| Preferred Name | Carbonic anhydrase 3 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P07451 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Carbonic anhydrase 3 |
| UniProt Accession | P07451 |
| Component Type | Protein |
| Sequence Length | 260 aa |
Carbonic anhydrase 3
Review this target as Carbonic anhydrase 3, mapped to UniProt P07451. Sequence length is 260 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL19 | 8.96 | Ki | 1.1 | Approved |
| CHEMBL20 | 8.51 | Ki | 3.1 | Approved |
| CHEMBL4562296 | 8.17 | Kd | 6.7 | Preclinical |
| CHEMBL4165570 | 8.12 | Kd | 7.5 | Preclinical |
| CHEMBL4170792 | 8.12 | Kd | 7.6 | Preclinical |
| CHEMBL120886 | 8.08 | Kd | 8.4 | Preclinical |
| CHEMBL4161701 | 8.02 | Kd | 9.6 | Preclinical |
| CHEMBL4442511 | 8.0 | Kd | 10.0 | Preclinical |
| CHEMBL4578934 | 7.92 | Kd | 12.0 | Preclinical |
| CHEMBL4437818 | 7.89 | Kd | 13.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 74 | 144 | 5.2 |
| assay format | 10 | 90 | 6.0 |
| cell-based format | 6 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 20 | 5.8 |