Protein kinase C gamma type · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P05129. Use UniProt P05129 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P05129 as the stable identity anchor, then attach disease evidence before program review.
Protein kinase C gamma type
Review this target as Protein kinase C gamma type, mapped to UniProt P05129. Sequence length is 697 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Protein kinase C gamma type as ChEMBL target CHEMBL2938, mapped to UniProt P05129. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Protein kinase C gamma type is the right protein anchor across sources, using UniProt P05129 as the stable mapping.
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| Preferred Name | Protein kinase C gamma type |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P05129 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Protein kinase C gamma type |
| UniProt Accession | P05129 |
| Component Type | Protein |
| Sequence Length | 697 aa |
Protein kinase C gamma type
Review this target as Protein kinase C gamma type, mapped to UniProt P05129. Sequence length is 697 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL337834 | 9.8 | Kd | 0.16 | Preclinical |
| CHEMBL2148106 | 9.42 | Ki | 0.38 | Preclinical |
| CHEMBL388978 | 9.27 | IC50 | 0.542 | Preclinical |
| CHEMBL1256416 | 9.2 | Ki | 0.63 | Preclinical |
| CHEMBL5175742 | 9.19 | Ki | 0.65 | Preclinical |
| CHEMBL2418196 | 9.16 | Ki | 0.69 | Preclinical |
| CHEMBL285801 | 8.92 | Ki | 1.2 | Preclinical |
| CHEMBL27768 | 8.92 | Kd | 1.19 | Preclinical |
| CHEMBL337834 | 8.82 | Ki | 1.5 | Preclinical |
| CHEMBL27768 | 8.8 | Ki | 1.58 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 273 | 197 | 6.7 |
| cell-based format | 24 | 5 | 5.8 |
| assay format | 20 | 4 | 7.7 |
| cell membrane format | 1 | 4 | 7.3 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 5 | 166 | 5.9 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 0 | — |