Glutathione hydrolase 1 proenzyme · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt P07314. Use UniProt P07314 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P07314 as the stable identity anchor, then attach disease evidence before program review.
Glutathione hydrolase 1 proenzyme
Review this target as Glutathione hydrolase 1 proenzyme, mapped to UniProt P07314. Sequence length is 568 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Glutathione hydrolase 1 proenzyme as ChEMBL target CHEMBL2943, mapped to UniProt P07314. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Glutathione hydrolase 1 proenzyme is the right protein anchor across sources, using UniProt P07314 as the stable mapping.
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| Preferred Name | Glutathione hydrolase 1 proenzyme |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P07314 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Glutathione hydrolase 1 proenzyme |
| UniProt Accession | P07314 |
| Component Type | Protein |
| Sequence Length | 568 aa |
Glutathione hydrolase 1 proenzyme
Review this target as Glutathione hydrolase 1 proenzyme, mapped to UniProt P07314. Sequence length is 568 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL11298 | 4.3 | Ki | 50000.0 | Clinical |
| CHEMBL116299 | 4.28 | Ki | 53000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 11 | 6 | 4.3 |
| assay format | 5 | 0 | — |
| single protein format | 3 | 1 | 4.3 |