Carbonic anhydrase 6 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P23280. Use UniProt P23280 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P23280 as the stable identity anchor, then attach disease evidence before program review.
Carbonic anhydrase 6
Review this target as Carbonic anhydrase 6, mapped to UniProt P23280. Sequence length is 308 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Carbonic anhydrase 6 as ChEMBL target CHEMBL3025, mapped to UniProt P23280. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Carbonic anhydrase 6 is the right protein anchor across sources, using UniProt P23280 as the stable mapping.
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| Preferred Name | Carbonic anhydrase 6 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P23280 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Carbonic anhydrase 6 |
| UniProt Accession | P23280 |
| Component Type | Protein |
| Sequence Length | 308 aa |
Carbonic anhydrase 6
Review this target as Carbonic anhydrase 6, mapped to UniProt P23280. Sequence length is 308 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4441730 | 10.17 | Kd | 0.067 | Preclinical |
| CHEMBL4573916 | 10.14 | Kd | 0.073 | Preclinical |
| CHEMBL68253 | 10.05 | Ki | 0.09 | Preclinical |
| CHEMBL4555622 | 10.04 | Kd | 0.092 | Preclinical |
| CHEMBL4475315 | 10.0 | Kd | 0.1 | Preclinical |
| CHEMBL4474251 | 9.92 | Kd | 0.12 | Preclinical |
| CHEMBL4517728 | 9.85 | Kd | 0.14 | Preclinical |
| CHEMBL4560953 | 9.82 | Kd | 0.15 | Preclinical |
| CHEMBL4463683 | 9.8 | Kd | 0.16 | Preclinical |
| CHEMBL4462447 | 9.77 | Kd | 0.17 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 67 | 282 | 6.5 |
| assay format | 10 | 147 | 7.0 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 20 | 6.8 |