Cytochrome P450 2D3 · SINGLE PROTEIN · Rattus norvegicus
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P12938. Use UniProt P12938 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P12938 as the stable identity anchor, then attach disease evidence before program review.
Cytochrome P450 2D3
Review this target as Cytochrome P450 2D3, mapped to UniProt P12938. Sequence length is 500 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cytochrome P450 2D3 as ChEMBL target CHEMBL3057, mapped to UniProt P12938. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Cytochrome P450 2D3 is the right protein anchor across sources, using UniProt P12938 as the stable mapping.
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| Preferred Name | Cytochrome P450 2D3 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P12938 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cytochrome P450 2D3 |
| UniProt Accession | P12938 |
| Component Type | Protein |
| Sequence Length | 500 aa |
Cytochrome P450 2D3
Review this target as Cytochrome P450 2D3, mapped to UniProt P12938. Sequence length is 500 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL170 | 4.92 | IC50 | 12000.0 | Approved |
| CHEMBL445 | 4.85 | IC50 | 14200.0 | Approved |
| CHEMBL52440 | 4.73 | IC50 | 18600.0 | Approved |
| CHEMBL1294 | 4.57 | IC50 | 26900.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 11 | 4.8 |