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Target Snapshot

CHEMBL3061 Target Snapshot

Phosphodiesterase 3A · SINGLE PROTEIN · Sus scrofa

12Compounds
11Assays
2Approved Drugs
16.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Protein identity stays anchored to UniProt Q9XSW7. Use UniProt Q9XSW7 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q9XSW7 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Phosphodiesterase 3A as ChEMBL target CHEMBL3061, mapped to UniProt Q9XSW7. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Phosphodiesterase 3A
SINGLE PROTEIN · Sus scrofa
As of 2026-09-13
ChEMBL target ID
CHEMBL3061
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
UniProt accession
Q9XSW7
Phosphodiesterase
UniProt accession via ChEMBL component mapping As of 2026-09-13
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Phosphodiesterase 3A is the right protein anchor across sources, using UniProt Q9XSW7 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelPhosphodiesterase
UniProt AccessionQ9XSW7
Component TypeProtein
Sequence Length985 aa

Phosphodiesterase

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Phosphodiesterase 3A, mapped to UniProt Q9XSW7. ChEMBL maps the protein component as Phosphodiesterase. Sequence length is 985 aa.

Mapped IDQ9XSW7
Review namePhosphodiesterase 3A
OrganismSus scrofa
Clinical Profile

Clinical Phase Distribution

2
Approved
1
Phase III
Assay Mix

Activity Type Distribution

IC5016.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL302299 6.44 IC50 360.0 Preclinical
CHEMBL19224 6.21 IC50 620.0 Clinical
CHEMBL189 6.07 IC50 843.0 Approved
CHEMBL545712 4.76 IC50 17500.0 Preclinical
CHEMBL932 4.36 IC50 44000.0 Approved
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
3
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

MILRINONE
CHEMBL189
Approved 1987
Assay Landscape

Assay Landscape

11
Total Assays
5
Tested Compounds
1
Assay Types
Binding — 11 assays, 5 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 6 2 6.3
assay format 5 3 5.1

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine