Proto-oncogene tyrosine-protein kinase Src · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt P05480. Use UniProt P05480 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P05480 as the stable identity anchor, then attach disease evidence before program review.
Proto-oncogene tyrosine-protein kinase Src
Review this target as Proto-oncogene tyrosine-protein kinase Src, mapped to UniProt P05480. Sequence length is 535 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Proto-oncogene tyrosine-protein kinase Src as ChEMBL target CHEMBL3074, mapped to UniProt P05480. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Proto-oncogene tyrosine-protein kinase Src |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P05480 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Proto-oncogene tyrosine-protein kinase Src |
| UniProt Accession | P05480 |
| Component Type | Protein |
| Sequence Length | 535 aa |
Proto-oncogene tyrosine-protein kinase Src
Review this target as Proto-oncogene tyrosine-protein kinase Src, mapped to UniProt P05480. Sequence length is 535 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL49120 | 8.05 | IC50 | 9.0 | Preclinical |
| CHEMBL112914 | 7.77 | IC50 | 17.0 | Preclinical |
| CHEMBL136106 | 7.51 | IC50 | 31.0 | Preclinical |
| CHEMBL140242 | 7.3 | IC50 | 50.0 | Preclinical |
| CHEMBL4297299 | 7.22 | IC50 | 60.0 | Preclinical |
| CHEMBL136244 | 6.85 | IC50 | 140.0 | Preclinical |
| CHEMBL139249 | 6.8 | IC50 | 160.0 | Preclinical |
| CHEMBL341579 | 6.8 | IC50 | 160.0 | Preclinical |
| CHEMBL136280 | 6.75 | IC50 | 180.0 | Preclinical |
| CHEMBL136332 | 6.68 | IC50 | 210.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 13 | 42 | 4.7 |
| single protein format | 1 | 24 | 6.4 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| organism-based format | 3 | 0 | — |