Aldo-keto reductase family 1 member B1 · SINGLE PROTEIN · Bos taurus
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Move to another high-traffic target or paste a specific ChEMBL target ID.
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-13Protein identity stays anchored to UniProt P16116. Use UniProt P16116 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P16116 as the stable identity anchor, then attach disease evidence before program review.
Aldo-keto reductase family 1 member B1
Review this target as Aldo-keto reductase family 1 member B1, mapped to UniProt P16116. Sequence length is 315 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Aldo-keto reductase family 1 member B1 as ChEMBL target CHEMBL3081, mapped to UniProt P16116. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Aldo-keto reductase family 1 member B1 is the right protein anchor across sources, using UniProt P16116 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Aldo-keto reductase family 1 member B1 |
| Target Type | SINGLE PROTEIN |
| Organism | Bos taurus |
| UniProt | P16116 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Aldo-keto reductase family 1 member B1 |
| UniProt Accession | P16116 |
| Component Type | Protein |
| Sequence Length | 315 aa |
Aldo-keto reductase family 1 member B1
Review this target as Aldo-keto reductase family 1 member B1, mapped to UniProt P16116. Sequence length is 315 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL7679 | 8.15 | IC50 | 7.0 | Clinical |
| CHEMBL292963 | 8.05 | IC50 | 9.0 | Preclinical |
| CHEMBL142239 | 8.05 | IC50 | 9.0 | Preclinical |
| CHEMBL64091 | 8.01 | IC50 | 9.7 | Preclinical |
| CHEMBL358284 | 7.96 | IC50 | 11.0 | Preclinical |
| CHEMBL273910 | 7.85 | IC50 | 14.0 | Clinical |
| CHEMBL292486 | 7.82 | IC50 | 15.0 | Preclinical |
| CHEMBL358825 | 7.82 | IC50 | 15.0 | Preclinical |
| CHEMBL62478 | 7.77 | IC50 | 17.0 | Preclinical |
| CHEMBL64543 | 7.75 | IC50 | 18.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 125 | 317 | 5.5 |
| tissue-based format | 5 | 3 | 4.7 |
| organism-based format | 3 | 0 | — |
| assay format | 1 | 4 | 5.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 15 | 7.3 |