Alpha-1B adrenergic receptor · SINGLE PROTEIN · Mesocricetus auratus
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As of 2026-09-13Protein identity stays anchored to UniProt P18841. Use UniProt P18841 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P18841 as the stable identity anchor, then attach disease evidence before program review.
Alpha-1B adrenergic receptor
Review this target as Alpha-1B adrenergic receptor, mapped to UniProt P18841. Sequence length is 515 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Alpha-1B adrenergic receptor as ChEMBL target CHEMBL3122, mapped to UniProt P18841. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Alpha-1B adrenergic receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Mesocricetus auratus |
| UniProt | P18841 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Alpha-1B adrenergic receptor |
| UniProt Accession | P18841 |
| Component Type | Protein |
| Sequence Length | 515 aa |
Alpha-1B adrenergic receptor
Review this target as Alpha-1B adrenergic receptor, mapped to UniProt P18841. Sequence length is 515 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1259113 | 10.41 | Ki | 0.039 | Preclinical |
| CHEMBL1259144 | 10.09 | Ki | 0.081 | Preclinical |
| CHEMBL1259112 | 10.06 | Ki | 0.088 | Preclinical |
| CHEMBL1259042 | 9.77 | Ki | 0.17 | Preclinical |
| CHEMBL836 | 9.7 | Ki | 0.2 | Approved |
| CHEMBL1258987 | 9.7 | Ki | 0.2 | Preclinical |
| CHEMBL1259190 | 9.7 | Ki | 0.2 | Preclinical |
| CHEMBL303313 | 9.66 | Ki | 0.22 | Preclinical |
| CHEMBL1259232 | 9.6 | Ki | 0.25 | Preclinical |
| CHEMBL1259023 | 9.59 | Ki | 0.26 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 8 | 73 | 7.0 |
| cell-based format | 5 | 64 | 8.2 |