85/88 kDa calcium-independent phospholipase A2 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt O60733. Use UniProt O60733 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O60733 as the stable identity anchor, then attach disease evidence before program review.
85/88 kDa calcium-independent phospholipase A2
Review this target as 85/88 kDa calcium-independent phospholipase A2, mapped to UniProt O60733. Sequence length is 806 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats 85/88 kDa calcium-independent phospholipase A2 as ChEMBL target CHEMBL3213, mapped to UniProt O60733. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | 85/88 kDa calcium-independent phospholipase A2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O60733 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 85/88 kDa calcium-independent phospholipase A2 |
| UniProt Accession | O60733 |
| Component Type | Protein |
| Sequence Length | 806 aa |
85/88 kDa calcium-independent phospholipase A2
Review this target as 85/88 kDa calcium-independent phospholipase A2, mapped to UniProt O60733. Sequence length is 806 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4476476 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL6223 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL89506 | 7.34 | IC50 | 46.0 | Preclinical |
| CHEMBL148674 | 7.25 | IC50 | 56.0 | Clinical |
| CHEMBL4438490 | 7.05 | IC50 | 90.0 | Preclinical |
| CHEMBL269758 | 7.02 | IC50 | 95.0 | Preclinical |
| CHEMBL6206 | 6.85 | IC50 | 140.0 | Preclinical |
| CHEMBL6228 | 6.72 | IC50 | 190.0 | Preclinical |
| CHEMBL4439384 | 5.46 | IC50 | 3500.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 41 | 5 | 6.7 |
| cell-based format | 5 | 0 | — |
| tissue-based format | 1 | 4 | 7.0 |