C-8 sterol isomerase ERG2 · SINGLE PROTEIN · Saccharomyces cerevisiae S288c
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As of 2026-09-13Protein identity stays anchored to UniProt P32352. Use UniProt P32352 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P32352 as the stable identity anchor, then attach disease evidence before program review.
C-8 sterol isomerase ERG2
Review this target as C-8 sterol isomerase ERG2, mapped to UniProt P32352. Sequence length is 222 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats C-8 sterol isomerase ERG2 as ChEMBL target CHEMBL3224, mapped to UniProt P32352. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | C-8 sterol isomerase ERG2 |
| Target Type | SINGLE PROTEIN |
| Organism | Saccharomyces cerevisiae S288c |
| UniProt | P32352 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | C-8 sterol isomerase ERG2 |
| UniProt Accession | P32352 |
| Component Type | Protein |
| Sequence Length | 222 aa |
C-8 sterol isomerase ERG2
Review this target as C-8 sterol isomerase ERG2, mapped to UniProt P32352. Sequence length is 222 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL372700 | 10.3 | Ki | 0.05 | Preclinical |
| CHEMBL365842 | 10.05 | Ki | 0.09 | Preclinical |
| CHEMBL15023 | 9.82 | Ki | 0.15 | Clinical |
| CHEMBL365141 | 9.7 | Ki | 0.2 | Preclinical |
| CHEMBL17470 | 9.4 | Ki | 0.4 | Preclinical |
| CHEMBL54 | 9.3 | Ki | 0.5 | Approved |
| CHEMBL190631 | 9.15 | Ki | 0.7 | Preclinical |
| CHEMBL113830 | 9.0 | Ki | 1.0 | Preclinical |
| CHEMBL167779 | 8.7 | Ki | 2.0 | Clinical |
| CHEMBL187709 | 8.7 | Ki | 2.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 11 | 40 | 7.2 |