Compound Detail
CHEMBL372700
FENPROPIMORPH Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL372700 |
| Name | FENPROPIMORPH |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RYAUSSKQMZRMAI-ALOPSCKCSA-N |
9
Targets
16
Activities
2
Assay Types
0
PK Parameters
20
Publications
0
Known Names
Molecular Properties
303.5
MW (Da)
4.27
ALogP
2
HBA
0
HBD
12.5
PSA (Ų)
0.82
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 13 meas. best 11.0
IC50 3 meas. best 6.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Sigma non-opioid intracellular receptor 1 CHEMBL287 | Ki | 11.0 | 9.62 | 0.0 | 3 |
| Sigma non-opioid intracellular receptor 1 CHEMBL3602 | Ki | 10.96 | 10.96 | 0.0 | 1 |
| Sigma non-opioid intracellular receptor 1 CHEMBL4153 | Ki | 10.96 | 10.6733 | 0.0 | 3 |
| C-8 sterol isomerase ERG2 CHEMBL3224 | Ki | 10.3 | 10.3 | 0.1 | 1 |
| 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase CHEMBL4931 | Ki | 7.52 | 7.52 | 30.0 | 1 |
| Cycloeucalenol cycloisomerase CHEMBL2366413 | IC50 | 6.4 | 6.4 | 400.0 | 1 |
| Sterol-8,7-isomerase CHEMBL2366492 | IC50 | 6.4 | 6.4 | 400.0 | 1 |
| Delta(14)-sterol reductase CHEMBL2366411 | IC50 | 6.1 | 6.1 | 800.0 | 1 |
| Sigma intracellular receptor 2 CHEMBL4105864 | Ki | 6.07 | 6.07 | 854.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Literature References
Data from ChEMBL 36 via Core Engine