Sigma non-opioid intracellular receptor 1 · SINGLE PROTEIN · Cavia porcellus
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Move to another high-traffic target or paste a specific ChEMBL target ID.
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-13Protein identity stays anchored to UniProt Q60492. Use UniProt Q60492 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q60492 as the stable identity anchor, then attach disease evidence before program review.
Sigma non-opioid intracellular receptor 1
Review this target as Sigma non-opioid intracellular receptor 1, mapped to UniProt Q60492. Sequence length is 223 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Sigma non-opioid intracellular receptor 1 as ChEMBL target CHEMBL4153, mapped to UniProt Q60492. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Sigma non-opioid intracellular receptor 1 is the right protein anchor across sources, using UniProt Q60492 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Sigma non-opioid intracellular receptor 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Cavia porcellus |
| UniProt | Q60492 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Sigma non-opioid intracellular receptor 1 |
| UniProt Accession | Q60492 |
| Component Type | Protein |
| Sequence Length | 223 aa |
Sigma non-opioid intracellular receptor 1
Review this target as Sigma non-opioid intracellular receptor 1, mapped to UniProt Q60492. Sequence length is 223 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL372700 | 10.96 | Ki | 0.011 | Preclinical |
| CHEMBL545278 | 10.52 | Ki | 0.03 | Preclinical |
| CHEMBL176941 | 10.52 | Ki | 0.03 | Preclinical |
| CHEMBL76758 | 10.44 | Ki | 0.036 | Preclinical |
| CHEMBL1917286 | 10.3 | Ki | 0.05 | Preclinical |
| CHEMBL304079 | 10.15 | Ki | 0.07 | Preclinical |
| CHEMBL4073530 | 10.1 | Ki | 0.08 | Preclinical |
| CHEMBL2069863 | 10.0 | Ki | 0.1 | Preclinical |
| CHEMBL573234 | 9.96 | Ki | 0.11 | Preclinical |
| CHEMBL2069865 | 9.92 | Ki | 0.12 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell membrane format | 200 | 1,689 | 7.4 |
| assay format | 55 | 745 | 7.3 |
| single protein format | 25 | 56 | 7.1 |
| tissue-based format | 24 | 192 | 7.2 |
| microsome format | 2 | 1 | 11.0 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell membrane format | 1 | 22 | 6.7 |
| single protein format | 1 | 1 | 5.7 |