Delta(14)-sterol reductase · SINGLE PROTEIN · Zea mays
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As of 2026-09-14Protein identity stays anchored to UniProt B4FS76. Use UniProt B4FS76 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt B4FS76 as the stable identity anchor, then attach disease evidence before program review.
Delta(14)-sterol reductase
Review this target as Delta(14)-sterol reductase, mapped to UniProt B4FS76. Sequence length is 370 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Delta(14)-sterol reductase as ChEMBL target CHEMBL2366411, mapped to UniProt B4FS76. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Delta(14)-sterol reductase |
| Target Type | SINGLE PROTEIN |
| Organism | Zea mays |
| UniProt | B4FS76 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Delta(14)-sterol reductase |
| UniProt Accession | B4FS76 |
| Component Type | Protein |
| Sequence Length | 370 aa |
Delta(14)-sterol reductase
Review this target as Delta(14)-sterol reductase, mapped to UniProt B4FS76. Sequence length is 370 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2253388 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL2253390 | 7.16 | IC50 | 70.0 | Preclinical |
| CHEMBL17413 | 7.1 | IC50 | 80.0 | Preclinical |
| CHEMBL279569 | 7.05 | IC50 | 90.0 | Preclinical |
| CHEMBL17470 | 6.52 | IC50 | 300.0 | Preclinical |
| CHEMBL372700 | 6.1 | IC50 | 800.0 | Preclinical |
| CHEMBL1889041 | 5.52 | IC50 | 3000.0 | Preclinical |
| CHEMBL333562 | 5.35 | IC50 | 4500.0 | Preclinical |
| CHEMBL2286765 | 4.6 | IC50 | 25000.0 | Preclinical |
| CHEMBL3215942 | 4.4 | IC50 | 40000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 10 | 6.1 |
| single protein format | 1 | 0 | — |