Assay Detail
Binding
CHEMBL3049783
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Zea mays (maize) cycloeucalenol-obtusifolial isomerase
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Zea mays |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Microsomal delta 8,14-sterol delta 14-reductase in higher plants. Characterization and inhibition by analogues of a presumptive carbocationic intermediate of the reduction reaction.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 6.61 | 7.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL17470 | — | — | 1 | 7.60 |
| CHEMBL2253390 | — | — | 1 | 7.00 |
| CHEMBL17413 | — | — | 1 | 7.00 |
| CHEMBL279569 | — | — | 1 | 7.00 |
| CHEMBL1889041 | FENPROPIDIN | -1.0 | 1 | 6.70 |
| CHEMBL2286765 | TRIDEMORPH | — | 1 | 6.40 |
| CHEMBL372700 | FENPROPIMORPH | — | 1 | 6.40 |
| CHEMBL333562 | — | — | 1 | 4.76 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL17470 | — | IC50 | = | 25.0 | nM | 7.60 |
| CHEMBL2253390 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL17413 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL279569 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL1889041 | FENPROPIDIN | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL2286765 | TRIDEMORPH | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL372700 | FENPROPIMORPH | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL333562 | — | IC50 | = | 17500.0 | nM | 4.76 |