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Target Snapshot

CHEMBL3232693 Target Snapshot

CD44 antigen · SINGLE PROTEIN · Mus musculus

11Compounds
1Assays
0Approved Drugs
11.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt P15379. Use UniProt P15379 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt P15379 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats CD44 antigen as ChEMBL target CHEMBL3232693, mapped to UniProt P15379. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
CD44 antigen
SINGLE PROTEIN · Mus musculus
As of 2026-09-14
ChEMBL target ID
CHEMBL3232693
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
P15379
CD44 antigen
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether CD44 antigen is the right protein anchor across sources, using UniProt P15379 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelCD44 antigen
UniProt AccessionP15379
Component TypeProtein
Sequence Length778 aa

CD44 antigen

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as CD44 antigen, mapped to UniProt P15379. Sequence length is 778 aa.

Mapped IDP15379
Review nameCD44 antigen
OrganismMus musculus
Assay Mix

Activity Type Distribution

KD11.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL3237623 5.19 Kd 6400.0 Preclinical
CHEMBL3237622 4.66 Kd 21700.0 Preclinical
CHEMBL3237621 4.49 Kd 32700.0 Preclinical
CHEMBL3237620 4.23 Kd 58400.0 Preclinical
CHEMBL3237627 3.3 Kd 500000.0 Preclinical
CHEMBL3237624 2.96 Kd 1100000.0 Preclinical
CHEMBL3237626 2.26 Kd 5500000.0 Preclinical
CHEMBL3183504 2.19 Kd 6400000.0 Preclinical
Distribution

pChEMBL Value Distribution

1
5.0
0
5.5
0
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

1
Total Assays
11
Tested Compounds
1
Assay Types
Binding — 1 assays, 11 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 1 11 3.7

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine