Compound Detail
CHEMBL3237620
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Basic Information
| ChEMBL ID | CHEMBL3237620 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XPUFUQLOOZFGID-GFAJNXTCSA-N |
2
Targets
3
Activities
2
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
1156.0
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 2 meas. best 4.41
IC50 1 meas.
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| CD44 antigen CHEMBL3232692 | Kd | 4.41 | 4.41 | 38800.0 | 1 |
| CD44 antigen CHEMBL3232693 | Kd | 4.23 | 4.23 | 58400.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| CD44 antigen | Kd | = | 38800.0 | nM | 4.41 | Binding affinity to immobilized recombinant human CD44 hyaluronan binding domain... | 24606063 |
| CD44 antigen | Kd | = | 58400.0 | nM | 4.23 | Binding affinity to immobilized recombinant mouse CD44 hyaluronan binding domain... | 24606063 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24606063 | 10.1021/jm5000276 | CD44 antigen | 3 |
Data from ChEMBL 36 via Core Engine