Amine oxidase [flavin-containing] A · SINGLE PROTEIN · Bos taurus
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As of 2026-09-13Protein identity stays anchored to UniProt P21398. Use UniProt P21398 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P21398 as the stable identity anchor, then attach disease evidence before program review.
Amine oxidase [flavin-containing] A
Review this target as Amine oxidase [flavin-containing] A, mapped to UniProt P21398. Sequence length is 527 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Amine oxidase [flavin-containing] A as ChEMBL target CHEMBL3254, mapped to UniProt P21398. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Amine oxidase [flavin-containing] A |
| Target Type | SINGLE PROTEIN |
| Organism | Bos taurus |
| UniProt | P21398 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Amine oxidase [flavin-containing] A |
| UniProt Accession | P21398 |
| Component Type | Protein |
| Sequence Length | 527 aa |
Amine oxidase [flavin-containing] A
Review this target as Amine oxidase [flavin-containing] A, mapped to UniProt P21398. Sequence length is 527 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2178425 | 11.0 | Ki | 0.0101 | Preclinical |
| CHEMBL2178990 | 10.96 | Ki | 0.011 | Preclinical |
| CHEMBL2178984 | 10.96 | Ki | 0.0109 | Preclinical |
| CHEMBL2178986 | 10.95 | Ki | 0.0112 | Preclinical |
| CHEMBL2178988 | 10.92 | Ki | 0.012 | Preclinical |
| CHEMBL1939851 | 9.22 | Ki | 0.6 | Preclinical |
| CHEMBL1939853 | 9.1 | Ki | 0.8 | Preclinical |
| CHEMBL460599 | 9.04 | Ki | 0.92 | Preclinical |
| CHEMBL375966 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL212501 | 9.0 | Ki | 1.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 10 | 137 | 7.3 |
| mitochondrion format | 8 | 141 | 7.0 |
| single protein format | 6 | 37 | 5.8 |