Neuronal nicotinic acetylcholine receptor · PROTEIN COMPLEX GROUP · Mus musculus
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Move to another high-traffic target or paste a specific ChEMBL target ID.
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt Q9ERK7. Use UniProt Q9ERK7 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9ERK7 as the stable identity anchor, then attach disease evidence before program review.
Neuronal acetylcholine receptor subunit beta-2
Review this target as Neuronal nicotinic acetylcholine receptor, mapped to UniProt Q9ERK7. ChEMBL maps the protein component as Neuronal acetylcholine receptor subunit beta-2. Sequence length is 501 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Neuronal nicotinic acetylcholine receptor as ChEMBL target CHEMBL3350222, mapped to UniProt Q9ERK7. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Neuronal nicotinic acetylcholine receptor is the right protein anchor across sources, using UniProt Q9ERK7 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Neuronal nicotinic acetylcholine receptor |
| Target Type | PROTEIN COMPLEX GROUP |
| Organism | Mus musculus |
| UniProt | Q9ERK7 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Neuronal acetylcholine receptor subunit beta-2 |
| UniProt Accession | Q9ERK7 |
| Component Type | Protein |
| Sequence Length | 501 aa |
Neuronal acetylcholine receptor subunit beta-2
Review this target as Neuronal nicotinic acetylcholine receptor, mapped to UniProt Q9ERK7. ChEMBL maps the protein component as Neuronal acetylcholine receptor subunit beta-2. Sequence length is 501 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3 | 8.92 | Ki | 1.2 | Approved |
| CHEMBL294757 | 8.74 | Ki | 1.8 | Preclinical |
| CHEMBL111659 | 8.52 | IC50 | 3.0 | Clinical |
| CHEMBL3 | 8.4 | IC50 | 4.0 | Approved |
| CHEMBL111580 | 8.34 | IC50 | 4.6 | Preclinical |
| CHEMBL103225 | 8.25 | Ki | 5.6 | Preclinical |
| CHEMBL111526 | 7.96 | IC50 | 11.0 | Preclinical |
| CHEMBL61772 | 7.72 | IC50 | 19.0 | Preclinical |
| CHEMBL320023 | 7.68 | Ki | 21.0 | Preclinical |
| CHEMBL103537 | 7.66 | Ki | 22.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein complex format | 3 | 9 | 8.1 |
| cell membrane format | 1 | 6 | 8.0 |