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Target Snapshot

CHEMBL3351200 Target Snapshot

Kinesin-like protein KIFC1 · SINGLE PROTEIN · Homo sapiens

85Compounds
27Assays
0Approved Drugs
88.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Protein identity stays anchored to UniProt Q9BW19. Use UniProt Q9BW19 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q9BW19 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Kinesin-like protein KIFC1 as ChEMBL target CHEMBL3351200, mapped to UniProt Q9BW19. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Kinesin-like protein KIFC1
SINGLE PROTEIN · Homo sapiens
As of 2026-09-13
ChEMBL target ID
CHEMBL3351200
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
UniProt accession
Q9BW19
Kinesin-like protein KIFC1
UniProt accession via ChEMBL component mapping As of 2026-09-13
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Kinesin-like protein KIFC1 is the right protein anchor across sources, using UniProt Q9BW19 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelKinesin-like protein KIFC1
UniProt AccessionQ9BW19
Component TypeProtein
Sequence Length673 aa

Kinesin-like protein KIFC1

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Kinesin-like protein KIFC1, mapped to UniProt Q9BW19. Sequence length is 673 aa.

Mapped IDQ9BW19
Review nameKinesin-like protein KIFC1
OrganismHomo sapiens
Clinical Profile

Clinical Phase Distribution

1
Phase II
1
Phase 0.5
Assay Mix

Activity Type Distribution

IC5082.0
KD6.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL5399029 7.96 IC50 11.0 Preclinical
CHEMBL5432943 7.92 IC50 12.0 Preclinical
CHEMBL5410651 7.89 IC50 13.0 Preclinical
CHEMBL5402640 7.72 IC50 19.0 Preclinical
CHEMBL5424226 7.57 IC50 27.0 Preclinical
CHEMBL5413808 7.41 IC50 39.0 Preclinical
CHEMBL5437239 7.21 IC50 61.0 Preclinical
CHEMBL5408867 7.2 IC50 63.0 Preclinical
CHEMBL5402097 7.05 IC50 89.0 Preclinical
CHEMBL5401191 7.03 IC50 93.0 Preclinical
Distribution

pChEMBL Value Distribution

5
5.0
12
5.5
11
6.0
17
6.5
10
7.0
5
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

27
Total Assays
60
Tested Compounds
1
Assay Types
Binding — 27 assays, 60 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 14 0
single protein format 12 31 6.6
assay format 1 29 5.7

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine