Liver carboxylesterase · SINGLE PROTEIN · Sus scrofa
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As of 2026-09-13Protein identity stays anchored to UniProt Q29550. Use UniProt Q29550 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q29550 as the stable identity anchor, then attach disease evidence before program review.
Liver carboxylesterase
Review this target as Liver carboxylesterase, mapped to UniProt Q29550. Sequence length is 566 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Liver carboxylesterase as ChEMBL target CHEMBL3383, mapped to UniProt Q29550. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Liver carboxylesterase is the right protein anchor across sources, using UniProt Q29550 as the stable mapping.
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| Preferred Name | Liver carboxylesterase |
| Target Type | SINGLE PROTEIN |
| Organism | Sus scrofa |
| UniProt | Q29550 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Liver carboxylesterase |
| UniProt Accession | Q29550 |
| Component Type | Protein |
| Sequence Length | 566 aa |
Liver carboxylesterase
Review this target as Liver carboxylesterase, mapped to UniProt Q29550. Sequence length is 566 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL155514 | 9.34 | IC50 | 0.4571 | Preclinical |
| CHEMBL270374 | 8.89 | IC50 | 1.3 | Preclinical |
| CHEMBL440542 | 8.74 | IC50 | 1.8 | Preclinical |
| CHEMBL89506 | 8.62 | IC50 | 2.4 | Preclinical |
| CHEMBL269931 | 8.49 | IC50 | 3.2 | Preclinical |
| CHEMBL402615 | 8.35 | IC50 | 4.5 | Preclinical |
| CHEMBL4854298 | 8.3 | IC50 | 4.95 | Preclinical |
| CHEMBL4868014 | 8.29 | IC50 | 5.14 | Preclinical |
| CHEMBL270375 | 8.28 | IC50 | 5.3 | Preclinical |
| CHEMBL4853742 | 8.21 | IC50 | 6.14 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 34 | 1 | 5.8 |
| tissue-based format | 9 | 0 | — |
| single protein format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 26 | 84 | 6.1 |
| tissue-based format | 6 | 22 | 7.1 |
| single protein format | 1 | 21 | 6.6 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| small-molecule physicochemical format | 1 | 0 | — |