Induced myeloid leukemia cell differentiation protein Mcl-1/BH3-interacting domain death agonist · PROTEIN-PROTEIN INTERACTION · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q07820. Use UniProt Q07820 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q07820 as the stable identity anchor, then attach disease evidence before program review.
Induced myeloid leukemia cell differentiation protein Mcl-1
Review this target as Induced myeloid leukemia cell differentiation protein Mcl-1/BH3-interacting domain death agonist, mapped to UniProt Q07820. ChEMBL maps the protein component as Induced myeloid leukemia cell differentiation protein Mcl-1. Sequence length is 350 aa.
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This review treats Induced myeloid leukemia cell differentiation protein Mcl-1/BH3-interacting domain death agonist as ChEMBL target CHEMBL3430886, mapped to UniProt Q07820. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Induced myeloid leukemia cell differentiation protein Mcl-1/BH3-interacting domain death agonist |
| Target Type | PROTEIN-PROTEIN INTERACTION |
| Organism | Homo sapiens |
| UniProt | Q07820 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Induced myeloid leukemia cell differentiation protein Mcl-1 |
| UniProt Accession | Q07820 |
| Component Type | Protein |
| Sequence Length | 350 aa |
Induced myeloid leukemia cell differentiation protein Mcl-1
Review this target as Induced myeloid leukemia cell differentiation protein Mcl-1/BH3-interacting domain death agonist, mapped to UniProt Q07820. ChEMBL maps the protein component as Induced myeloid leukemia cell differentiation protein Mcl-1. Sequence length is 350 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1272170 | 7.6 | IC50 | 25.0 | Preclinical |
| CHEMBL4848284 | 7.24 | Ki | 58.0 | Preclinical |
| CHEMBL5198484 | 6.97 | Ki | 106.0 | Preclinical |
| CHEMBL4589399 | 6.7 | Ki | 200.0 | Preclinical |
| CHEMBL476921 | 6.7 | Ki | 200.0 | Preclinical |
| CHEMBL5204188 | 6.54 | Ki | 290.0 | Preclinical |
| CHEMBL5183108 | 6.5 | Ki | 320.0 | Preclinical |
| CHEMBL5090868 | 6.48 | Ki | 330.0 | Preclinical |
| CHEMBL5181865 | 6.44 | Ki | 360.0 | Preclinical |
| CHEMBL5206049 | 6.38 | Ki | 420.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein format | 14 | 53 | 5.7 |