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Target Snapshot

CHEMBL3562168 Target Snapshot

Putative P2Y purinoceptor 10 · SINGLE PROTEIN · Mus musculus

113Compounds
9Assays
0Approved Drugs
223.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-15

Protein identity stays anchored to UniProt Q8BFU7. Use UniProt Q8BFU7 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q8BFU7 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-15
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Putative P2Y purinoceptor 10 as ChEMBL target CHEMBL3562168, mapped to UniProt Q8BFU7. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Putative P2Y purinoceptor 10
SINGLE PROTEIN · Mus musculus
As of 2026-09-15
ChEMBL target ID
CHEMBL3562168
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-15
www.ebi.ac.uk
UniProt accession
Q8BFU7
Putative P2Y purinoceptor 10
UniProt accession via ChEMBL component mapping As of 2026-09-15
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-15
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Putative P2Y purinoceptor 10 is the right protein anchor across sources, using UniProt Q8BFU7 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelPutative P2Y purinoceptor 10
UniProt AccessionQ8BFU7
Component TypeProtein
Sequence Length328 aa

Putative P2Y purinoceptor 10

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Putative P2Y purinoceptor 10, mapped to UniProt Q8BFU7. Sequence length is 328 aa.

Mapped IDQ8BFU7
Review namePutative P2Y purinoceptor 10
OrganismMus musculus
Assay Mix

Activity Type Distribution

EC50223.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL4753103 9.01 EC50 0.9772 Preclinical
CHEMBL5421007 9.01 EC50 0.9772 Preclinical
CHEMBL5402557 8.96 EC50 1.1 Preclinical
CHEMBL3577262 8.82 EC50 1.5 Preclinical
CHEMBL5437846 8.8 EC50 1.6 Preclinical
CHEMBL5396462 8.73 EC50 1.862 Preclinical
CHEMBL5426296 8.59 EC50 2.57 Preclinical
CHEMBL5393782 8.57 EC50 2.7 Preclinical
CHEMBL5424029 8.53 EC50 2.951 Preclinical
CHEMBL5434445 8.43 EC50 3.7 Preclinical
Distribution

pChEMBL Value Distribution

1
5.0
10
5.5
28
6.0
32
6.5
26
7.0
30
7.5
16
8.0
12
8.5
4
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

9
Total Assays
45
Tested Compounds
2
Assay Types
Binding — 7 assays, 34 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 7 34 6.9
Functional — 2 assays, 45 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 2 45 7.4

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine