Compound Detail
CHEMBL5393782
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5393782 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LJOQGFFOKBMFJO-QHCPKHFHSA-N |
2
Targets
4
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
544.6
MW (Da)
4.41
ALogP
8
HBA
3
HBD
160.4
PSA (Ų)
0.10
QED
1
Ro5 Violations
23
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 4 meas. best 8.57
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Putative P2Y purinoceptor 10 CHEMBL3562168 | EC50 | 8.57 | 8.565 | 2.7 | 2 |
| Probable G-protein coupled receptor 34 CHEMBL1075291 | EC50 | 5.8 | 5.795 | 1600.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Putative P2Y purinoceptor 10 | EC50 | = | 2.7 | nM | 8.57 | Agonist activity at mouse LPS2/P2Y10 transfected in HEK293-A cells co-transfecte... | 36965226 |
| Putative P2Y purinoceptor 10 | EC50 | = | 2.754 | nM | 8.56 | Agonist activity at mouse LPS2/P2Y10 transfected in HEK293-A cells co-transfecte... | 36965226 |
| Probable G-protein coupled receptor 34 | EC50 | = | 1600.0 | nM | 5.8 | Agonist activity at mouse LPS1/GPR34 transfected in HEK293-A cells co-transfecte... | 36965226 |
| Probable G-protein coupled receptor 34 | EC50 | = | 1621.81 | nM | 5.79 | Agonist activity at mouse LPS1/GPR34 transfected in HEK293-A cells co-transfecte... | 36965226 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 36965226 | 10.1016/j.ejmech.2023.115271 | Probable G-protein coupled receptor 34 | 3 |
| 36965226 | 10.1016/j.ejmech.2023.115271 | Putative P2Y purinoceptor 10 | 3 |
Data from ChEMBL 36 via Core Engine