Corticotropin-releasing factor receptor 2 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-13Protein identity stays anchored to UniProt P47866. Use UniProt P47866 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P47866 as the stable identity anchor, then attach disease evidence before program review.
Corticotropin-releasing factor receptor 2
Review this target as Corticotropin-releasing factor receptor 2, mapped to UniProt P47866. Sequence length is 411 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Corticotropin-releasing factor receptor 2 as ChEMBL target CHEMBL3581, mapped to UniProt P47866. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Corticotropin-releasing factor receptor 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P47866 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Corticotropin-releasing factor receptor 2 |
| UniProt Accession | P47866 |
| Component Type | Protein |
| Sequence Length | 411 aa |
Corticotropin-releasing factor receptor 2
Review this target as Corticotropin-releasing factor receptor 2, mapped to UniProt P47866. Sequence length is 411 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2370918 | 9.24 | IC50 | 0.57 | Preclinical |
| CHEMBL4299295 | 9.2 | EC50 | 0.63 | Preclinical |
| CHEMBL3774395 | 9.11 | EC50 | 0.77 | Preclinical |
| CHEMBL3774939 | 9.04 | EC50 | 0.91 | Preclinical |
| CHEMBL3775796 | 9.0 | EC50 | 1.0 | Preclinical |
| CHEMBL3775217 | 9.0 | EC50 | 1.0 | Preclinical |
| CHEMBL440057 | 8.68 | IC50 | 2.07 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 1 | 0 | — |
| tissue-based format | 1 | 2 | 9.0 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 5 | 9.1 |