Ghrelin O-acyltransferase · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q96T53. Use UniProt Q96T53 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q96T53 as the stable identity anchor, then attach disease evidence before program review.
Membrane-bound ghrelin O-acyltransferase MBOAT4
Review this target as Ghrelin O-acyltransferase, mapped to UniProt Q96T53. ChEMBL maps the protein component as Membrane-bound ghrelin O-acyltransferase MBOAT4. Sequence length is 435 aa.
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This review treats Ghrelin O-acyltransferase as ChEMBL target CHEMBL3588729, mapped to UniProt Q96T53. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Ghrelin O-acyltransferase |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q96T53 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Membrane-bound ghrelin O-acyltransferase MBOAT4 |
| UniProt Accession | Q96T53 |
| Component Type | Protein |
| Sequence Length | 435 aa |
Membrane-bound ghrelin O-acyltransferase MBOAT4
Review this target as Ghrelin O-acyltransferase, mapped to UniProt Q96T53. ChEMBL maps the protein component as Membrane-bound ghrelin O-acyltransferase MBOAT4. Sequence length is 435 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4793203 | 10.7 | IC50 | 0.02 | Preclinical |
| CHEMBL6065698 | 10.7 | IC50 | 0.02 | Preclinical |
| CHEMBL5779713 | 10.66 | IC50 | 0.022 | Preclinical |
| CHEMBL5961160 | 10.59 | IC50 | 0.026 | Preclinical |
| CHEMBL6019672 | 10.59 | IC50 | 0.026 | Preclinical |
| CHEMBL5776289 | 10.57 | IC50 | 0.027 | Preclinical |
| CHEMBL6006052 | 10.57 | IC50 | 0.027 | Preclinical |
| CHEMBL4746798 | 10.55 | IC50 | 0.028 | Preclinical |
| CHEMBL6011632 | 10.52 | IC50 | 0.03 | Preclinical |
| CHEMBL5854761 | 10.48 | IC50 | 0.033 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 7 | 12 | 6.8 |
| single protein format | 5 | 15 | 6.8 |
| assay format | 4 | 244 | 9.2 |
| cell membrane format | 3 | 8 | 6.5 |
| microsome format | 1 | 2 | 8.4 |