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Target Snapshot

CHEMBL3611961 Target Snapshot

Mu opioid receptor-like OR2 · SINGLE PROTEIN · Danio rerio

17Compounds
2Assays
1Approved Drugs
18.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt Q98UH1. Use UniProt Q98UH1 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q98UH1 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Mu opioid receptor-like OR2 as ChEMBL target CHEMBL3611961, mapped to UniProt Q98UH1. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Mu opioid receptor-like OR2
SINGLE PROTEIN · Danio rerio
As of 2026-09-14
ChEMBL target ID
CHEMBL3611961
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
Q98UH1
Mu-type opioid receptor
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Mu opioid receptor-like OR2 is the right protein anchor across sources, using UniProt Q98UH1 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelMu-type opioid receptor
UniProt AccessionQ98UH1
Component TypeProtein
Sequence Length384 aa

Mu-type opioid receptor

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Mu opioid receptor-like OR2, mapped to UniProt Q98UH1. ChEMBL maps the protein component as Mu-type opioid receptor. Sequence length is 384 aa.

Mapped IDQ98UH1
Review nameMu opioid receptor-like OR2
OrganismDanio rerio
Clinical Profile

Clinical Phase Distribution

1
Approved
Assay Mix

Activity Type Distribution

KI18.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL70 6.73 Ki 187.0 Approved
CHEMBL4101712 6.69 Ki 202.5 Preclinical
CHEMBL4083712 6.65 Ki 223.1 Preclinical
CHEMBL4064725 6.62 Ki 239.4 Preclinical
CHEMBL4095111 6.57 Ki 269.0 Preclinical
CHEMBL4065055 6.5 Ki 312.6 Preclinical
CHEMBL4102609 6.42 Ki 383.3 Preclinical
CHEMBL13786 6.17 Ki 684.0 Preclinical
CHEMBL8234 5.88 Ki 1317.0 Preclinical
CHEMBL3612241 5.08 Ki 8240.0 Preclinical
Distribution

pChEMBL Value Distribution

2
5.0
1
5.5
2
6.0
7
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

MORPHINE
CHEMBL70
Approved 1984
Assay Landscape

Assay Landscape

2
Total Assays
17
Tested Compounds
1
Assay Types
Binding — 2 assays, 17 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 2 17 5.6

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine