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Target Snapshot

CHEMBL3632454 Target Snapshot

Kinesin-like protein KIF15 · SINGLE PROTEIN · Homo sapiens

32Compounds
20Assays
0Approved Drugs
5.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt Q9NS87. Use UniProt Q9NS87 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q9NS87 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Kinesin-like protein KIF15 as ChEMBL target CHEMBL3632454, mapped to UniProt Q9NS87. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Kinesin-like protein KIF15
SINGLE PROTEIN · Homo sapiens
As of 2026-09-14
ChEMBL target ID
CHEMBL3632454
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
Q9NS87
Kinesin-like protein KIF15
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Kinesin-like protein KIF15 is the right protein anchor across sources, using UniProt Q9NS87 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelKinesin-like protein KIF15
UniProt AccessionQ9NS87
Component TypeProtein
Sequence Length1388 aa

Kinesin-like protein KIF15

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Kinesin-like protein KIF15, mapped to UniProt Q9NS87. Sequence length is 1388 aa.

Mapped IDQ9NS87
Review nameKinesin-like protein KIF15
OrganismHomo sapiens
Assay Mix

Activity Type Distribution

IC505.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL4540278 6.7 IC50 200.0 Preclinical
CHEMBL73157 6.12 IC50 750.0 Preclinical
CHEMBL72365 5.6 IC50 2500.0 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
2
5.5
2
6.0
1
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

20
Total Assays
4
Tested Compounds
1
Assay Types
Binding — 20 assays, 4 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 10 3 6.1
assay format 7 1 5.8
single protein format 3 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine