Use UniProt Q0GKD7 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL3693 Target Snapshot
Farnesyl pyrophosphate synthase · SINGLE PROTEIN · Leishmania donovani
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As of 2026-09-13Protein identity stays anchored to UniProt Q0GKD7. Use UniProt Q0GKD7 as the stable identity anchor, then attach disease evidence before program review.
Farnesyl pyrophosphate synthase
Review this target as Farnesyl pyrophosphate synthase, mapped to UniProt Q0GKD7. Sequence length is 362 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Farnesyl pyrophosphate synthase as ChEMBL target CHEMBL3693, mapped to UniProt Q0GKD7. Disease framing currently uses the Open Targets-ready proxy contract.
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Open Review-ready CardBasic Information
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| Preferred Name | Farnesyl pyrophosphate synthase |
| Target Type | SINGLE PROTEIN |
| Organism | Leishmania donovani |
| UniProt | Q0GKD7 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Farnesyl pyrophosphate synthase |
| UniProt Accession | Q0GKD7 |
| Component Type | Protein |
| Sequence Length | 362 aa |
Farnesyl pyrophosphate synthase
How to read this target
Review this target as Farnesyl pyrophosphate synthase, mapped to UniProt Q0GKD7. Sequence length is 362 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL192342 | 8.05 | Ki | 9.0 | Preclinical |
| CHEMBL4303669 | 7.96 | Ki | 11.0 | Approved |
| CHEMBL923 | 7.77 | Ki | 17.0 | Approved |
| CHEMBL191634 | 7.75 | Ki | 18.0 | Preclinical |
| CHEMBL192043 | 7.7 | Ki | 20.0 | Preclinical |
| CHEMBL373332 | 7.7 | Ki | 20.0 | Preclinical |
| CHEMBL363145 | 7.52 | Ki | 30.0 | Preclinical |
| CHEMBL193356 | 7.42 | Ki | 38.0 | Preclinical |
| CHEMBL193722 | 7.3 | Ki | 50.0 | Preclinical |
| CHEMBL192938 | 7.16 | Ki | 70.0 | Preclinical |
pChEMBL Value Distribution
Approved Drugs
Assay Landscape
Binding — 3 assays, 59 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 3 | 59 | 6.0 |