Methyl-CpG-binding domain protein 2 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9UBB5. Use UniProt Q9UBB5 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9UBB5 as the stable identity anchor, then attach disease evidence before program review.
Methyl-CpG-binding domain protein 2
Review this target as Methyl-CpG-binding domain protein 2, mapped to UniProt Q9UBB5. Sequence length is 411 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Methyl-CpG-binding domain protein 2 as ChEMBL target CHEMBL3707462, mapped to UniProt Q9UBB5. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Methyl-CpG-binding domain protein 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9UBB5 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Methyl-CpG-binding domain protein 2 |
| UniProt Accession | Q9UBB5 |
| Component Type | Protein |
| Sequence Length | 411 aa |
Methyl-CpG-binding domain protein 2
Review this target as Methyl-CpG-binding domain protein 2, mapped to UniProt Q9UBB5. Sequence length is 411 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3687963 | 7.96 | IC50 | 11.0 | Preclinical |
| CHEMBL3687966 | 6.68 | IC50 | 210.0 | Preclinical |
| CHEMBL3687965 | 6.33 | IC50 | 470.0 | Preclinical |
| CHEMBL520851 | 6.17 | IC50 | 670.0 | Preclinical |
| CHEMBL3687961 | 5.81 | IC50 | 1550.0 | Preclinical |
| CHEMBL489770 | 5.81 | IC50 | 1550.0 | Preclinical |
| CHEMBL3687962 | 5.21 | IC50 | 6140.0 | Preclinical |
| CHEMBL3687964 | 4.42 | IC50 | 38000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 8 | 6.0 |