Use UniProt P11216 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL3856 Target Snapshot
Glycogen phosphorylase, brain form · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P11216. Use UniProt P11216 as the stable identity anchor, then attach disease evidence before program review.
Glycogen phosphorylase, brain form
Review this target as Glycogen phosphorylase, brain form, mapped to UniProt P11216. Sequence length is 843 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Glycogen phosphorylase, brain form as ChEMBL target CHEMBL3856, mapped to UniProt P11216. Disease framing currently uses the Open Targets-ready proxy contract.
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Open Review-ready CardBasic Information
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| Preferred Name | Glycogen phosphorylase, brain form |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P11216 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Glycogen phosphorylase, brain form |
| UniProt Accession | P11216 |
| Component Type | Protein |
| Sequence Length | 843 aa |
Glycogen phosphorylase, brain form
How to read this target
Review this target as Glycogen phosphorylase, brain form, mapped to UniProt P11216. Sequence length is 843 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL335077 | 7.5 | Ki | 31.62 | Preclinical |
| CHEMBL3752910 | 7.4 | Kd | 39.46 | Preclinical |
| CHEMBL3351153 | 6.8 | Ki | 158.49 | Preclinical |
| CHEMBL3351144 | 5.52 | Ki | 3000.0 | Preclinical |
| CHEMBL97548 | 5.51 | Ki | 3100.0 | Preclinical |
| CHEMBL428690 | 5.45 | Kd | 3569.0 | Clinical |
| CHEMBL489798 | 5.29 | Ki | 5100.0 | Preclinical |
| CHEMBL5653589 | 5.16 | Kd | 6995.82 | Preclinical |
| CHEMBL133097 | 4.8 | Ki | 15848.93 | Preclinical |
| CHEMBL319614 | 4.8 | Ki | 16000.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 14 assays, 137 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 8 | 122 | 4.7 |
| assay format | 2 | 2 | 4.9 |
| tissue-based format | 2 | 12 | 4.9 |
| cell-based format | 1 | 0 | — |
| subcellular format | 1 | 1 | 5.5 |