Compound Detail
CHEMBL97548
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Basic Information
| ChEMBL ID | CHEMBL97548 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QRXBDPYWCAAAAI-SJFCMNACSA-N |
1
Targets
5
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
248.2
MW (Da)
-4.00
ALogP
7
HBA
6
HBD
148.3
PSA (Ų)
0.26
QED
1
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 5 meas. best 5.51
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glycogen phosphorylase, brain form CHEMBL3856 | Ki | 5.51 | 5.028 | 3100.0 | 5 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glycogen phosphorylase, brain form | Ki | = | 3100.0 | nM | 5.51 | Inhibitory activity against muscle Glycogen Phosphorylase b | 11495595 |
| Glycogen phosphorylase, brain form | Ki | = | 4200.0 | nM | 5.38 | Inhibitory activity against muscle Glycogen Phosphorylase b | 11495595 |
| Glycogen phosphorylase, brain form | Ki | = | 12800.0 | nM | 4.89 | Inhibitory activity against liver Glycogen Phosphorylase b | 11495595 |
| Glycogen phosphorylase, brain form | Ki | = | 16500.0 | nM | 4.78 | Inhibitory activity against liver Glycogen Phosphorylase a | 11495595 |
| Glycogen phosphorylase, brain form | Ki | = | 26000.0 | nM | 4.58 | Inhibitory activity against muscle Glycogen Phosphorylase a | 11495595 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11495595 | 10.1021/jm010892t | Glycogen phosphorylase, brain form | 5 |
Data from ChEMBL 36 via Core Engine