Carnitine O-palmitoyltransferase 1, liver isoform · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-13Protein identity stays anchored to UniProt P32198. Use UniProt P32198 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P32198 as the stable identity anchor, then attach disease evidence before program review.
Carnitine O-palmitoyltransferase 1, liver isoform
Review this target as Carnitine O-palmitoyltransferase 1, liver isoform, mapped to UniProt P32198. Sequence length is 773 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Carnitine O-palmitoyltransferase 1, liver isoform as ChEMBL target CHEMBL3858, mapped to UniProt P32198. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Carnitine O-palmitoyltransferase 1, liver isoform |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P32198 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Carnitine O-palmitoyltransferase 1, liver isoform |
| UniProt Accession | P32198 |
| Component Type | Protein |
| Sequence Length | 773 aa |
Carnitine O-palmitoyltransferase 1, liver isoform
Review this target as Carnitine O-palmitoyltransferase 1, liver isoform, mapped to UniProt P32198. Sequence length is 773 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3431816 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL3431837 | 8.18 | IC50 | 6.6 | Preclinical |
| CHEMBL3431815 | 8.14 | IC50 | 7.2 | Preclinical |
| CHEMBL3431629 | 8.01 | IC50 | 9.7 | Preclinical |
| CHEMBL3431830 | 8.0 | IC50 | 10.1 | Preclinical |
| CHEMBL3431832 | 8.0 | IC50 | 10.1 | Preclinical |
| CHEMBL3431642 | 7.95 | IC50 | 11.2 | Preclinical |
| CHEMBL3431678 | 7.94 | IC50 | 11.5 | Preclinical |
| CHEMBL3431628 | 7.92 | IC50 | 11.9 | Preclinical |
| CHEMBL3431820 | 7.92 | IC50 | 12.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| mitochondrion format | 10 | 21 | 5.9 |
| assay format | 8 | 469 | 6.8 |
| single protein format | 5 | 4 | 4.6 |
| cell-based format | 2 | 2 | 5.9 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 2 | 5.4 |