Serine/threonine-protein kinase D1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q15139. Use UniProt Q15139 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q15139 as the stable identity anchor, then attach disease evidence before program review.
Serine/threonine-protein kinase D1
Review this target as Serine/threonine-protein kinase D1, mapped to UniProt Q15139. Sequence length is 912 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Serine/threonine-protein kinase D1 as ChEMBL target CHEMBL3863, mapped to UniProt Q15139. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Serine/threonine-protein kinase D1 is the right protein anchor across sources, using UniProt Q15139 as the stable mapping.
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| Preferred Name | Serine/threonine-protein kinase D1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q15139 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Serine/threonine-protein kinase D1 |
| UniProt Accession | Q15139 |
| Component Type | Protein |
| Sequence Length | 912 aa |
Serine/threonine-protein kinase D1
Review this target as Serine/threonine-protein kinase D1, mapped to UniProt Q15139. Sequence length is 912 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1215711 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL1214998 | 9.22 | IC50 | 0.6 | Preclinical |
| CHEMBL4113471 | 9.05 | Ki | 0.9 | Preclinical |
| CHEMBL1214711 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL1214712 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL1214860 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL1214999 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL1215000 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL1215001 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL1215002 | 9.0 | IC50 | 1.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 284 | 150 | 7.1 |
| assay format | 38 | 10 | 8.0 |
| cell-based format | 28 | 26 | 6.0 |
| subcellular format | 6 | 0 | — |