Rhodopsin kinase GRK1 · SINGLE PROTEIN · Bos taurus
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As of 2026-09-14Protein identity stays anchored to UniProt P28327. Use UniProt P28327 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P28327 as the stable identity anchor, then attach disease evidence before program review.
Rhodopsin kinase GRK1
Review this target as Rhodopsin kinase GRK1, mapped to UniProt P28327. Sequence length is 561 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Rhodopsin kinase GRK1 as ChEMBL target CHEMBL3879860, mapped to UniProt P28327. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Rhodopsin kinase GRK1 is the right protein anchor across sources, using UniProt P28327 as the stable mapping.
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| Preferred Name | Rhodopsin kinase GRK1 |
| Target Type | SINGLE PROTEIN |
| Organism | Bos taurus |
| UniProt | P28327 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Rhodopsin kinase GRK1 |
| UniProt Accession | P28327 |
| Component Type | Protein |
| Sequence Length | 561 aa |
Rhodopsin kinase GRK1
Review this target as Rhodopsin kinase GRK1, mapped to UniProt P28327. Sequence length is 561 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL463931 | 6.89 | IC50 | 130.0 | Preclinical |
| CHEMBL4456539 | 6.12 | IC50 | 760.0 | Preclinical |
| CHEMBL4475305 | 5.68 | IC50 | 2100.0 | Preclinical |
| CHEMBL60254 | 5.39 | IC50 | 4100.0 | Preclinical |
| CHEMBL1738878 | 5.04 | IC50 | 9100.0 | Preclinical |
| CHEMBL517171 | 4.89 | IC50 | 13000.0 | Preclinical |
| CHEMBL4098656 | 4.61 | IC50 | 24500.0 | Preclinical |
| CHEMBL4063014 | 4.59 | IC50 | 25800.0 | Preclinical |
| CHEMBL4090923 | 4.5 | IC50 | 32000.0 | Preclinical |
| CHEMBL1738877 | 4.28 | IC50 | 52100.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 7 | 16 | 5.0 |