Corticotropin-releasing factor receptor 2/Corticotropin-releasing factor-binding protein · PROTEIN COMPLEX · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q13324. Use UniProt Q13324 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q13324 as the stable identity anchor, then attach disease evidence before program review.
Corticotropin-releasing factor receptor 2
Review this target as Corticotropin-releasing factor receptor 2/Corticotropin-releasing factor-binding protein, mapped to UniProt Q13324. ChEMBL maps the protein component as Corticotropin-releasing factor receptor 2. Sequence length is 411 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Corticotropin-releasing factor receptor 2/Corticotropin-releasing factor-binding protein as ChEMBL target CHEMBL3885546, mapped to UniProt Q13324. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Corticotropin-releasing factor receptor 2/Corticotropin-releasing factor-binding protein |
| Target Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
| UniProt | Q13324 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Corticotropin-releasing factor receptor 2 |
| UniProt Accession | Q13324 |
| Component Type | Protein |
| Sequence Length | 411 aa |
Corticotropin-releasing factor receptor 2
Review this target as Corticotropin-releasing factor receptor 2/Corticotropin-releasing factor-binding protein, mapped to UniProt Q13324. ChEMBL maps the protein component as Corticotropin-releasing factor receptor 2. Sequence length is 411 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1995565 | 6.34 | EC50 | 460.0 | Preclinical |
| CHEMBL1400385 | 6.3 | IC50 | 506.0 | Preclinical |
| CHEMBL1375451 | 6.26 | IC50 | 545.0 | Preclinical |
| CHEMBL1500274 | 6.26 | EC50 | 544.0 | Preclinical |
| CHEMBL1489517 | 6.21 | IC50 | 610.0 | Preclinical |
| CHEMBL1464584 | 6.15 | EC50 | 709.0 | Preclinical |
| CHEMBL1371902 | 6.14 | IC50 | 723.0 | Preclinical |
| CHEMBL1974381 | 6.14 | IC50 | 727.0 | Preclinical |
| CHEMBL1734544 | 6.12 | IC50 | 754.0 | Preclinical |
| CHEMBL1526609 | 6.1 | EC50 | 793.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 766 | 5.1 |