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Target Snapshot

CHEMBL3885564 Target Snapshot

Dipeptidyl peptidase 8/9 · PROTEIN FAMILY · Homo sapiens

59Compounds
8Assays
0Approved Drugs
77.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt Q6V1X1. Use UniProt Q6V1X1 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q6V1X1 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Dipeptidyl peptidase 8/9 as ChEMBL target CHEMBL3885564, mapped to UniProt Q6V1X1. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Dipeptidyl peptidase 8/9
PROTEIN FAMILY · Homo sapiens
As of 2026-09-14
ChEMBL target ID
CHEMBL3885564
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
Q6V1X1
Dipeptidyl peptidase 8
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Dipeptidyl peptidase 8/9 is the right protein anchor across sources, using UniProt Q6V1X1 as the stable mapping.

Jump to Protein Context
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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelDipeptidyl peptidase 8
UniProt AccessionQ6V1X1
Component TypeProtein
Sequence Length898 aa

Dipeptidyl peptidase 8

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Dipeptidyl peptidase 8/9, mapped to UniProt Q6V1X1. ChEMBL maps the protein component as Dipeptidyl peptidase 8. Sequence length is 898 aa.

Mapped IDQ6V1X1
Review nameDipeptidyl peptidase 8/9
OrganismHomo sapiens
Clinical Profile

Clinical Phase Distribution

1
Phase III
Assay Mix

Activity Type Distribution

IC5077.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL5968328 7.57 IC50 27.0 Preclinical
CHEMBL6004569 7.57 IC50 27.0 Preclinical
CHEMBL6014809 7.24 IC50 58.0 Preclinical
CHEMBL5848496 6.96 IC50 110.0 Preclinical
CHEMBL363250 6.92 IC50 120.0 Preclinical
CHEMBL3686733 6.87 IC50 135.0 Preclinical
CHEMBL5778991 6.57 IC50 270.0 Preclinical
CHEMBL66032 6.36 IC50 440.0 Preclinical
CHEMBL5957037 5.92 IC50 1200.0 Preclinical
CHEMBL6060914 5.7 IC50 2000.0 Preclinical
Distribution

pChEMBL Value Distribution

4
5.0
4
5.5
1
6.0
6
6.5
1
7.0
3
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

8
Total Assays
33
Tested Compounds
2
Assay Types
Binding — 7 assays, 33 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 4 0
protein format 3 33 5.7
ADME — 1 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 1 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine