Compound Detail
CHEMBL6060914
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Basic Information
| ChEMBL ID | CHEMBL6060914 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CFPVWYBIFIRQLW-GFCCVEGCSA-N |
5
Targets
5
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
250.3
MW (Da)
2.04
ALogP
2
HBA
1
HBD
46.3
PSA (Ų)
0.83
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 5 meas. best 8.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Dipeptidyl peptidase 8 CHEMBL4657 | IC50 | 8.52 | 8.52 | 3.0 | 1 |
| Dipeptidyl peptidase 9 CHEMBL4793 | IC50 | 8.18 | 8.18 | 6.6 | 1 |
| Dipeptidyl peptidase 8/9 CHEMBL3885564 | IC50 | 5.7 | 5.7 | 2000.0 | 1 |
| Dipeptidyl peptidase 4 CHEMBL284 | IC50 | 5.01 | 5.01 | 9818.0 | 1 |
| Dipeptidyl peptidase 2 CHEMBL3976 | IC50 | 4.43 | 4.43 | 36840.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Dipeptidyl peptidase 8 | IC50 | = | 3.0 | nM | 8.52 | EnPlex (purified enzyme activity assay): This assay is described in Bachovchin e... | - |
| Dipeptidyl peptidase 9 | IC50 | = | 6.6 | nM | 8.18 | EnPlex (purified enzyme activity assay): This assay is described in Bachovchin e... | - |
| Dipeptidyl peptidase 8/9 | IC50 | = | 2000.0 | nM | 5.7 | EnPlex (purified enzyme activity assay): This assay is described in Bachovchin e... | - |
| Dipeptidyl peptidase 4 | IC50 | = | 9818.0 | nM | 5.01 | EnPlex (purified enzyme activity assay): This assay is described in Bachovchin e... | - |
| Dipeptidyl peptidase 2 | IC50 | = | 36840.0 | nM | 4.43 | EnPlex (purified enzyme activity assay): This assay is described in Bachovchin e... | - |
Data from ChEMBL 36 via Core Engine