Polymerase acidic protein /RNA-directed RNA polymerase catalytic subunit · PROTEIN-PROTEIN INTERACTION · Influenza A virus (strain A/Wilson-Smith/1933 H1N1)
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Move to another high-traffic target or paste a specific ChEMBL target ID.
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P15659. Use UniProt P15659 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P15659 as the stable identity anchor, then attach disease evidence before program review.
Polymerase acidic protein
Review this target as Polymerase acidic protein /RNA-directed RNA polymerase catalytic subunit, mapped to UniProt P15659. ChEMBL maps the protein component as Polymerase acidic protein. Sequence length is 716 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Polymerase acidic protein /RNA-directed RNA polymerase catalytic subunit as ChEMBL target CHEMBL3885620, mapped to UniProt P15659. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Polymerase acidic protein /RNA-directed RNA polymerase catalytic subunit is the right protein anchor across sources, using UniProt P15659 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Polymerase acidic protein /RNA-directed RNA polymerase catalytic subunit |
| Target Type | PROTEIN-PROTEIN INTERACTION |
| Organism | Influenza A virus (strain A/Wilson-Smith/1933 H1N1) |
| UniProt | P15659 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Polymerase acidic protein |
| UniProt Accession | P15659 |
| Component Type | Protein |
| Sequence Length | 716 aa |
Polymerase acidic protein
Review this target as Polymerase acidic protein /RNA-directed RNA polymerase catalytic subunit, mapped to UniProt P15659. ChEMBL maps the protein component as Polymerase acidic protein. Sequence length is 716 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3915821 | 8.74 | IC50 | 1.8 | Preclinical |
| CHEMBL3981816 | 8.2 | IC50 | 6.3 | Preclinical |
| CHEMBL3955138 | 7.86 | IC50 | 13.9 | Preclinical |
| CHEMBL3964090 | 7.78 | IC50 | 16.6 | Preclinical |
| CHEMBL3954115 | 7.67 | IC50 | 21.64 | Preclinical |
| CHEMBL3973799 | 7.66 | IC50 | 21.7 | Preclinical |
| CHEMBL3110332 | 7.36 | IC50 | 43.32 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 7 | 7.9 |