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Target Snapshot

CHEMBL3916 Target Snapshot

Acetylcholine receptor subunit delta · SINGLE PROTEIN · Torpedo californica

25Compounds
16Assays
1Approved Drugs
13.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Protein identity stays anchored to UniProt P02718. Use UniProt P02718 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt P02718 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Acetylcholine receptor subunit delta as ChEMBL target CHEMBL3916, mapped to UniProt P02718. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Acetylcholine receptor subunit delta
SINGLE PROTEIN · Torpedo californica
As of 2026-09-13
ChEMBL target ID
CHEMBL3916
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
UniProt accession
P02718
Acetylcholine receptor subunit delta
UniProt accession via ChEMBL component mapping As of 2026-09-13
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

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Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Acetylcholine receptor subunit delta is the right protein anchor across sources, using UniProt P02718 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelAcetylcholine receptor subunit delta
UniProt AccessionP02718
Component TypeProtein
Sequence Length522 aa

Acetylcholine receptor subunit delta

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Acetylcholine receptor subunit delta, mapped to UniProt P02718. Sequence length is 522 aa.

Mapped IDP02718
Review nameAcetylcholine receptor subunit delta
OrganismTorpedo californica
Clinical Profile

Clinical Phase Distribution

1
Approved
1
Phase III
1
Phase II
Assay Mix

Activity Type Distribution

KI1.0
EC5012.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL6623 10.0 Ki 0.1 Preclinical
CHEMBL334809 7.0 EC50 100.0 Preclinical
CHEMBL6623 6.7 EC50 200.0 Preclinical
CHEMBL667 5.3 EC50 5000.0 Approved
CHEMBL1788226 5.1 EC50 8000.0 Preclinical
CHEMBL84149 4.72 EC50 19000.0 Preclinical
CHEMBL127071 4.52 EC50 30000.0 Clinical
CHEMBL497939 4.0 EC50 100000.0 Clinical
Distribution

pChEMBL Value Distribution

2
5.0
0
5.5
0
6.0
1
6.5
1
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

16
Total Assays
9
Tested Compounds
2
Assay Types
Binding — 12 assays, 9 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 9 7 5.1
cell-based format 2 2 5.9
cell membrane format 1 0
Functional — 4 assays, 2 compounds
BAO Format Assays Compounds Avg pChEMBL
assay format 4 2 6.5

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine