Use UniProt P02718 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL3916 Target Snapshot
Acetylcholine receptor subunit delta · SINGLE PROTEIN · Torpedo californica
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As of 2026-09-13Protein identity stays anchored to UniProt P02718. Use UniProt P02718 as the stable identity anchor, then attach disease evidence before program review.
Acetylcholine receptor subunit delta
Review this target as Acetylcholine receptor subunit delta, mapped to UniProt P02718. Sequence length is 522 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Acetylcholine receptor subunit delta as ChEMBL target CHEMBL3916, mapped to UniProt P02718. Disease framing currently uses the Open Targets-ready proxy contract.
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Open Review-ready CardBasic Information
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| Preferred Name | Acetylcholine receptor subunit delta |
| Target Type | SINGLE PROTEIN |
| Organism | Torpedo californica |
| UniProt | P02718 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Acetylcholine receptor subunit delta |
| UniProt Accession | P02718 |
| Component Type | Protein |
| Sequence Length | 522 aa |
Acetylcholine receptor subunit delta
How to read this target
Review this target as Acetylcholine receptor subunit delta, mapped to UniProt P02718. Sequence length is 522 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL6623 | 10.0 | Ki | 0.1 | Preclinical |
| CHEMBL334809 | 7.0 | EC50 | 100.0 | Preclinical |
| CHEMBL6623 | 6.7 | EC50 | 200.0 | Preclinical |
| CHEMBL667 | 5.3 | EC50 | 5000.0 | Approved |
| CHEMBL1788226 | 5.1 | EC50 | 8000.0 | Preclinical |
| CHEMBL84149 | 4.72 | EC50 | 19000.0 | Preclinical |
| CHEMBL127071 | 4.52 | EC50 | 30000.0 | Clinical |
| CHEMBL497939 | 4.0 | EC50 | 100000.0 | Clinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 12 assays, 9 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 9 | 7 | 5.1 |
| cell-based format | 2 | 2 | 5.9 |
| cell membrane format | 1 | 0 | — |
Functional — 4 assays, 2 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 4 | 2 | 6.5 |