Compound Detail
CHEMBL334809
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Basic Information
| ChEMBL ID | CHEMBL334809 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LKJAZPPERYANQL-UHFFFAOYSA-M |
| Parent Compound | CHEMBL151349 |
| Active Moiety | CHEMBL151349 |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
154.2
MW (Da)
0.98
ALogP
1
HBA
0
HBD
17.1
PSA (Ų)
0.51
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 7.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Acetylcholine receptor subunit delta CHEMBL3916 | EC50 | 7.0 | 7.0 | 100.0 | 1 |
| Neuronal acetylcholine receptor CHEMBL2094110 | EC50 | 4.0 | 4.0 | 100000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Acetylcholine receptor subunit delta | EC50 | = | 100.0 | nM | 7.0 | Compound was evaluated for functional potency and efficacy at human muscle type ... | 9435889 |
| Neuronal acetylcholine receptor | EC50 | = | 100000.0 | nM | 4.0 | Compound was evaluated for functional potency and efficacy at rat Nicotinic acet... | 9435889 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 9435889 | 10.1021/jm970377o | Acetylcholine receptor subunit delta | 1 |
| 9435889 | 10.1021/jm970377o | Neuronal acetylcholine receptor | 1 |
Data from ChEMBL 36 via Core Engine