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Target Snapshot

CHEMBL3933 Target Snapshot

Prostaglandin D2 receptor · SINGLE PROTEIN · Mus musculus

101Compounds
14Assays
0Approved Drugs
209.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Protein identity stays anchored to UniProt P70263. Use UniProt P70263 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt P70263 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Prostaglandin D2 receptor as ChEMBL target CHEMBL3933, mapped to UniProt P70263. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Prostaglandin D2 receptor
SINGLE PROTEIN · Mus musculus
As of 2026-09-13
ChEMBL target ID
CHEMBL3933
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
UniProt accession
P70263
Prostaglandin D2 receptor
UniProt accession via ChEMBL component mapping As of 2026-09-13
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Prostaglandin D2 receptor is the right protein anchor across sources, using UniProt P70263 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelProstaglandin D2 receptor
UniProt AccessionP70263
Component TypeProtein
Sequence Length357 aa

Prostaglandin D2 receptor

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Prostaglandin D2 receptor, mapped to UniProt P70263. Sequence length is 357 aa.

Mapped IDP70263
Review nameProstaglandin D2 receptor
OrganismMus musculus
Assay Mix

Activity Type Distribution

IC50106.0
KI103.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL1813277 9.15 IC50 0.7 Preclinical
CHEMBL1915863 9.15 IC50 0.7 Preclinical
CHEMBL1915865 9.0 IC50 1.0 Preclinical
CHEMBL1813120 8.96 IC50 1.1 Preclinical
CHEMBL1819617 8.92 IC50 1.2 Preclinical
CHEMBL1915866 8.85 IC50 1.4 Preclinical
CHEMBL1915858 8.82 IC50 1.5 Preclinical
CHEMBL1813276 8.8 IC50 1.6 Preclinical
CHEMBL1813118 8.74 IC50 1.8 Preclinical
CHEMBL1813289 8.74 IC50 1.8 Preclinical
Distribution

pChEMBL Value Distribution

5
5.0
9
5.5
11
6.0
19
6.5
15
7.0
42
7.5
49
8.0
20
8.5
3
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

14
Total Assays
77
Tested Compounds
2
Assay Types
Binding — 9 assays, 77 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 5 12 6.1
cell-based format 4 65 7.5
Functional — 5 assays, 64 compounds
BAO Format Assays Compounds Avg pChEMBL
cell-based format 5 64 8.1

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine