Ribosyldihydronicotinamide dehydrogenase [quinone] · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P16083. Use UniProt P16083 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P16083 as the stable identity anchor, then attach disease evidence before program review.
Ribosyldihydronicotinamide dehydrogenase [quinone]
Review this target as Ribosyldihydronicotinamide dehydrogenase [quinone], mapped to UniProt P16083. Sequence length is 231 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Ribosyldihydronicotinamide dehydrogenase [quinone] as ChEMBL target CHEMBL3959, mapped to UniProt P16083. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Ribosyldihydronicotinamide dehydrogenase [quinone] is the right protein anchor across sources, using UniProt P16083 as the stable mapping.
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| Preferred Name | Ribosyldihydronicotinamide dehydrogenase [quinone] |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P16083 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Ribosyldihydronicotinamide dehydrogenase [quinone] |
| UniProt Accession | P16083 |
| Component Type | Protein |
| Sequence Length | 231 aa |
Ribosyldihydronicotinamide dehydrogenase [quinone]
Review this target as Ribosyldihydronicotinamide dehydrogenase [quinone], mapped to UniProt P16083. Sequence length is 231 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL300056 | 10.06 | Ki | 0.088 | Preclinical |
| CHEMBL300056 | 10.05 | IC50 | 0.08913 | Preclinical |
| CHEMBL300728 | 9.89 | IC50 | 0.1288 | Preclinical |
| CHEMBL300728 | 9.89 | Ki | 0.13 | Preclinical |
| CHEMBL52559 | 9.74 | Ki | 0.18 | Preclinical |
| CHEMBL52559 | 9.7 | IC50 | 0.1995 | Preclinical |
| CHEMBL511675 | 9.52 | IC50 | 0.302 | Preclinical |
| CHEMBL53622 | 9.51 | IC50 | 0.309 | Preclinical |
| CHEMBL53622 | 9.51 | Ki | 0.31 | Preclinical |
| CHEMBL1770214 | 9.41 | IC50 | 0.39 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 48 | 146 | 6.3 |
| cell-based format | 19 | 48 | 7.5 |
| assay format | 18 | 157 | 5.9 |
| microsome format | 2 | 0 | — |
| subcellular format | 1 | 35 | 5.8 |