Voltage-gated potassium channel subfamily A member 1/beta-1 · PROTEIN COMPLEX · Homo sapiens
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Move to another high-traffic target or paste a specific ChEMBL target ID.
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt Q09470. Use UniProt Q09470 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q09470 as the stable identity anchor, then attach disease evidence before program review.
Potassium voltage-gated channel subfamily A member 1
Review this target as Voltage-gated potassium channel subfamily A member 1/beta-1, mapped to UniProt Q09470. ChEMBL maps the protein component as Potassium voltage-gated channel subfamily A member 1. Sequence length is 495 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Voltage-gated potassium channel subfamily A member 1/beta-1 as ChEMBL target CHEMBL3988636, mapped to UniProt Q09470. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Voltage-gated potassium channel subfamily A member 1/beta-1 is the right protein anchor across sources, using UniProt Q09470 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Voltage-gated potassium channel subfamily A member 1/beta-1 |
| Target Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
| UniProt | Q09470 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Potassium voltage-gated channel subfamily A member 1 |
| UniProt Accession | Q09470 |
| Component Type | Protein |
| Sequence Length | 495 aa |
Potassium voltage-gated channel subfamily A member 1
Review this target as Voltage-gated potassium channel subfamily A member 1/beta-1, mapped to UniProt Q09470. ChEMBL maps the protein component as Potassium voltage-gated channel subfamily A member 1. Sequence length is 495 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL259345 | 5.05 | EC50 | 8900.0 | Preclinical |
| CHEMBL3980134 | 4.8 | IC50 | 16000.0 | Preclinical |
| CHEMBL408488 | 4.78 | EC50 | 16700.0 | Preclinical |
| CHEMBL3982574 | 4.52 | IC50 | 30000.0 | Preclinical |
| CHEMBL3974079 | 4.42 | IC50 | 38000.0 | Preclinical |
| CHEMBL3931900 | 4.39 | IC50 | 41000.0 | Preclinical |
| CHEMBL3957761 | 4.33 | IC50 | 47000.0 | Preclinical |
| CHEMBL3961121 | 4.3 | IC50 | 50000.0 | Preclinical |
| CHEMBL3920238 | 4.29 | IC50 | 51000.0 | Preclinical |
| CHEMBL3955143 | 4.23 | IC50 | 59000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 4 | 2 | 4.9 |
| assay format | 1 | 13 | 4.3 |