Beta-3 adrenergic receptor · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-13Protein identity stays anchored to UniProt P26255. Use UniProt P26255 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P26255 as the stable identity anchor, then attach disease evidence before program review.
Beta-3 adrenergic receptor
Review this target as Beta-3 adrenergic receptor, mapped to UniProt P26255. Sequence length is 400 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Beta-3 adrenergic receptor as ChEMBL target CHEMBL4031, mapped to UniProt P26255. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Beta-3 adrenergic receptor is the right protein anchor across sources, using UniProt P26255 as the stable mapping.
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| Preferred Name | Beta-3 adrenergic receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P26255 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Beta-3 adrenergic receptor |
| UniProt Accession | P26255 |
| Component Type | Protein |
| Sequence Length | 400 aa |
Beta-3 adrenergic receptor
Review this target as Beta-3 adrenergic receptor, mapped to UniProt P26255. Sequence length is 400 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL32670 | 9.03 | EC50 | 0.9333 | Preclinical |
| CHEMBL3128194 | 8.89 | EC50 | 1.3 | Preclinical |
| CHEMBL284782 | 8.66 | EC50 | 2.188 | Preclinical |
| CHEMBL32590 | 8.52 | EC50 | 3.0 | Preclinical |
| CHEMBL2012521 | 8.3 | EC50 | 5.0 | Preclinical |
| CHEMBL32586 | 8.25 | EC50 | 5.623 | Preclinical |
| CHEMBL421193 | 8.22 | IC50 | 6.0 | Preclinical |
| CHEMBL251372 | 8.19 | EC50 | 6.5 | Preclinical |
| CHEMBL221188 | 8.17 | EC50 | 6.8 | Preclinical |
| CHEMBL32933 | 8.14 | EC50 | 7.244 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 11 | 13 | 6.7 |
| assay format | 6 | 24 | 7.5 |
| tissue-based format | 5 | 5 | 7.6 |
| organism-based format | 2 | 0 | — |
| cell-free format | 1 | 0 | — |
| single protein format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| mitochondrion format | 6 | 0 | — |
| single protein format | 4 | 1 | 6.3 |
| tissue-based format | 1 | 0 | — |