Plasma kallikrein · SINGLE PROTEIN · Rattus norvegicus
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P14272. Use UniProt P14272 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P14272 as the stable identity anchor, then attach disease evidence before program review.
Plasma kallikrein
Review this target as Plasma kallikrein, mapped to UniProt P14272. Sequence length is 638 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Plasma kallikrein as ChEMBL target CHEMBL4105792, mapped to UniProt P14272. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Plasma kallikrein is the right protein anchor across sources, using UniProt P14272 as the stable mapping.
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| Preferred Name | Plasma kallikrein |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P14272 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Plasma kallikrein |
| UniProt Accession | P14272 |
| Component Type | Protein |
| Sequence Length | 638 aa |
Plasma kallikrein
Review this target as Plasma kallikrein, mapped to UniProt P14272. Sequence length is 638 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4075544 | 9.4 | Ki | 0.4 | Preclinical |
| CHEMBL4079711 | 9.05 | Ki | 0.9 | Preclinical |
| CHEMBL4093698 | 8.7 | Ki | 2.0 | Preclinical |
| CHEMBL5284671 | 8.54 | Ki | 2.9 | Preclinical |
| CHEMBL4059991 | 8.47 | Ki | 3.4 | Preclinical |
| CHEMBL4070056 | 8.26 | Ki | 5.5 | Preclinical |
| CHEMBL5287333 | 8.18 | Ki | 6.6 | Preclinical |
| CHEMBL4079260 | 7.96 | Ki | 11.0 | Preclinical |
| CHEMBL5287858 | 7.57 | Ki | 27.2 | Preclinical |
| CHEMBL4094403 | 7.52 | Ki | 30.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 10 | 8.4 |