DEP domain-containing mTOR-interacting protein · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q8TB45. Use UniProt Q8TB45 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q8TB45 as the stable identity anchor, then attach disease evidence before program review.
DEP domain-containing mTOR-interacting protein
Review this target as DEP domain-containing mTOR-interacting protein, mapped to UniProt Q8TB45. Sequence length is 409 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats DEP domain-containing mTOR-interacting protein as ChEMBL target CHEMBL4105866, mapped to UniProt Q8TB45. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether DEP domain-containing mTOR-interacting protein is the right protein anchor across sources, using UniProt Q8TB45 as the stable mapping.
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| Preferred Name | DEP domain-containing mTOR-interacting protein |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q8TB45 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | DEP domain-containing mTOR-interacting protein |
| UniProt Accession | Q8TB45 |
| Component Type | Protein |
| Sequence Length | 409 aa |
DEP domain-containing mTOR-interacting protein
Review this target as DEP domain-containing mTOR-interacting protein, mapped to UniProt Q8TB45. Sequence length is 409 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4076172 | 6.22 | IC50 | 600.0 | Preclinical |
| CHEMBL4082200 | 6.22 | IC50 | 600.0 | Preclinical |
| CHEMBL4064715 | 6.16 | IC50 | 700.0 | Preclinical |
| CHEMBL4060289 | 6.1 | IC50 | 800.0 | Preclinical |
| CHEMBL4078352 | 6.1 | IC50 | 800.0 | Preclinical |
| CHEMBL1898589 | 5.89 | IC50 | 1300.0 | Preclinical |
| CHEMBL4084658 | 5.89 | IC50 | 1300.0 | Preclinical |
| CHEMBL4864193 | 5.03 | Kd | 9300.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 24 | 7 | 6.1 |
| single protein format | 1 | 1 | 5.0 |