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Target Snapshot

CHEMBL4105924 Target Snapshot

ELAV-like protein 3 · SINGLE PROTEIN · Homo sapiens

6Compounds
1Assays
0Approved Drugs
6.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Protein identity stays anchored to UniProt Q14576. Use UniProt Q14576 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt Q14576 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats ELAV-like protein 3 as ChEMBL target CHEMBL4105924, mapped to UniProt Q14576. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
ELAV-like protein 3
SINGLE PROTEIN · Homo sapiens
As of 2026-09-13
ChEMBL target ID
CHEMBL4105924
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
UniProt accession
Q14576
ELAV-like protein 3
UniProt accession via ChEMBL component mapping As of 2026-09-13
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether ELAV-like protein 3 is the right protein anchor across sources, using UniProt Q14576 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelELAV-like protein 3
UniProt AccessionQ14576
Component TypeProtein
Sequence Length367 aa

ELAV-like protein 3

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as ELAV-like protein 3, mapped to UniProt Q14576. Sequence length is 367 aa.

Mapped IDQ14576
Review nameELAV-like protein 3
OrganismHomo sapiens
Clinical Profile

Clinical Phase Distribution

1
Phase III
1
Phase II
Assay Mix

Activity Type Distribution

IC506.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL36327 6.7 IC50 200.0 Preclinical
CHEMBL4088244 6.7 IC50 200.0 Preclinical
CHEMBL6246 6.22 IC50 600.0 Clinical
CHEMBL164 6.0 IC50 1000.0 Preclinical
CHEMBL312163 5.92 IC50 1200.0 Preclinical
CHEMBL50 5.75 IC50 1800.0 Clinical
Distribution

pChEMBL Value Distribution

0
5.0
2
5.5
2
6.0
2
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

1
Total Assays
6
Tested Compounds
1
Assay Types
Binding — 1 assays, 6 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 1 6 6.2

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine