Compound Detail
CHEMBL4088244
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
COc1cc(O)c2c(c1)O[C@H](c1cc(O)c(O)c(O)c1)[C@H](OC(=O)c1cc(O)c(O)c(O)c1)C2
Basic Information
| ChEMBL ID | CHEMBL4088244 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YNUCVHDPBKKFBD-DENIHFKCSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
472.4
MW (Da)
2.54
ALogP
11
HBA
7
HBD
186.4
PSA (Ų)
0.22
QED
2
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| ELAV-like protein 3 CHEMBL4105924 | IC50 | 6.7 | 6.7 | 200.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| ELAV-like protein 3 | IC50 | = | 200.0 | nM | 6.7 | Inhibition of ELAV3 (unknown origin)-artificial ARE complex formation after 30 m... | 28587461 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 28587461 | 10.1021/acs.jmedchem.6b01871 | ELAV-like protein 3 | 1 |
Data from ChEMBL 36 via Core Engine