Assay Detail
Binding
CHEMBL4018387
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Inhibition of ELAV3 (unknown origin)-artificial ARE complex formation after 30 mins in the presence of biotin-labeled RNA probe by chemiluminescence nucleic acid detection method
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Compounds Interfering with Embryonic Lethal Abnormal Vision (ELAV) Protein-RNA Complexes: An Avenue for Discovering New Drugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.22 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL36327 | EPICATECHIN GALLATE | — | 1 | 6.70 |
| CHEMBL4088244 | — | — | 1 | 6.70 |
| CHEMBL6246 | ELLAGIC ACID | 2.0 | 1 | 6.22 |
| CHEMBL164 | MYRICETIN | — | 1 | 6.00 |
| CHEMBL312163 | RHAMNETIN | — | 1 | 5.92 |
| CHEMBL50 | QUERCETIN | 3.0 | 1 | 5.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL36327 | EPICATECHIN GALLATE | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL4088244 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL6246 | ELLAGIC ACID | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL164 | MYRICETIN | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL312163 | RHAMNETIN | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL50 | QUERCETIN | IC50 | = | 1800.0 | nM | 5.75 |